Assessment of the Infectious Reservoir of Malaria (AFIRM)

The paucity of data on what governs human infectivity to mosquitoes is a critical knowledge gap hindering attempts to control and eliminate malaria through transmission reduction. We will establish a standardized framework for assessing population infectivity to mosquitoes and thus the infectious reservoir in different malaria endemic settings. This will enable identification of target populations and optimal timings for control efforts including malaria Transmission Blocking Vaccines (MTBV).

Funding:

  • Bill and Melinda Gates Foundation

Collaborators:

  • London School of Hygiene and Tropical Medicine
  • The Radboud University Nijmegen Medical Center, Nijmegen